Serum Bactericidal Assays To Evaluate Typhoidal and Nontyphoidal Salmonella Vaccines
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چکیده
منابع مشابه
Serum bactericidal assays to evaluate typhoidal and nontyphoidal Salmonella vaccines.
Invasive Salmonella infections for which improved or new vaccines are being developed include enteric fever caused by Salmonella enterica serovars Typhi, Paratyphi A, and Paratyphi B and sepsis and meningitis in young children in sub-Saharan Africa caused by nontyphoidal Salmonella (NTS) serovars, particularly S. enterica serovars Typhimurium and Enteritidis. Assays are needed to measure functi...
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Nontyphoidal Salmonella (NTS) invasive infections are an important cause of morbidity and mortality in sub-Saharan Africa. Several vaccines are in development to prevent these infections. We describe an NTS opsonophagocytic killing assay that uses HL-60 cells and baby rabbit complement to quantify functional antibodies elicited by candidate NTS vaccines.
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ABSTRACT The epidemiological studies indicate that the incidence of salmonellosis is increasing throughout the world. The uncontroled and unappropriate usage of antibiotics has been caused multi - drug resistance in these organisms, in recent years. In a cross-sectional descriptive study, 204 strains of typhoidal salmonella (T.S) and 114 strains of non-typhoidal salmonella (N.T.S) were exami...
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Geneva, Switzerland: World Health Organization; 2007. 6. Splettstoesser WD, Tomaso H, Al Dahouk S, Neubauer H, SchuffWerner P. Diagnostic procedures in tularaemia with special focus on molecular and immunological techniques. J Vet Med B Infect Dis Vet Public Health 2005;52:249–261. 7. Jones RM, Nicas M, Hubbard A, Sylvester MD, Reingold A. The infectious dose of Francisella tularensis (tularemi...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2014
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00115-14